HDAC3 Monoclonal Antibody

Size: 50μL, 100μL

Catalogue Numbers: RA11352-50, RA11352-100

Citations, Manuals and MSDS Available upon request.

Background: histone deacetylase 3 (HDAC3) Homo sapiens Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq, Jul 2008],

Condition: Ascitic fluid containing 0.03% sodium azide, 0.5% BSA, 50% glycerol.

Storage Instructions: -20°C/1 year

Applications: WB; IHC-p; IF (paraffin section) ; ELISA

Species Cross-Reactivity: Human

GeneID (Human): 8841

SWISS: O15379

Source: Mouse

Research Use Only