Driver: San Francisco is an entry in the long-running action racing series. The story, which is entirely different from the Wii version of the same name, takes place six months after the events in Driv3r. Protagonist undercover cop John Tanner and antagonist Charles Jericho have both survived the final shootout in Istanbul. Jericho is facing sentencing after being tried in San Francisco, but escapes his prison van. He is chased down by Tanner and his partner, Tobias Jones. During the pursuit, Tanner's vehicle is struck by a Big Rig and he ends up in the hospital in a coma. The majority of the game takes place in Tanner's coma-induced dream where he continues to track down Jericho.